MOTS-c is a mitochondrial-derived peptide encoded by the 12S rRNA gene of mitochondrial DNA. As a naturally occurring signaling molecule, it has become a focal point in research on mitochondrial communication, metabolic regulation, and cellular energy homeostasis.
Researchers have investigated MOTS-c for its ability to activate AMPK (AMP-activated protein kinase) and influence the folate-methionine cycle. Studies in preclinical models have explored its effects on glucose metabolism, insulin sensitivity, exercise physiology, and age-related metabolic decline. Its unique origin as a mitochondrial-encoded peptide makes it a valuable tool for studying retrograde mitochondrial signaling.
Each vial contains 10mg of lyophilized MOTS-c, synthesized under GMP conditions with purity exceeding 98% by HPLC analysis. Quality control includes mass spectrometry confirmation and endotoxin testing. Certificate of analysis available upon request.
Storage: Store lyophilized at -20°C. Reconstituted at 2-8°C, use within 60 days.
For research and laboratory use only.







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